Stereolitografi ile üç boyutlu (3B) olarak biyobaskılanmış yapay kalp kapakçıklarının biyouyumluluk özelliklerinin analizi

Ali Akpek
804 81

Öz


Geçen yıllar içerisinde organ transplantasyonu konusunda olan ihtiyaç sürekli olarak artmıştır. Organ nakline ihtiyaç sürekli olarak artarken organ bağısı sayısında ciddi bir artış gözlenmemiştir. Organ naklinin kendisini bir ihtiyaç olarak en çok belli ettiği alanlardan bir tanesi de kalp kapakçığı hastalıklarıdır. Biyoprostetik ve mekanik kalp kapakçıklarının kendi içerisinde pek çok sorun bulundurmakta bu nedenle yeterli tedaviyi sağlayamamaktadır. Bütün bu sebepler dolayısıyla doku mühendisliği aracılığı ile kişinin kendi kök hücreleri kullanarak oluşturulabilen, biyouyumluluğu yüksek yapay kalp kapakçıkları üretmek mecburidir. Bu çalışmada amaçlanan, kalp kapakçıkları hastalıklarında kullanılmak üzere stereolitografi yöntemi ile üretilmiş yapay bir kalp kapakçığı üretmektir. Stereolitografi yöntemi yüksek çözünürlüğe sahip son derece güçlü mekanik özelliklere sahip olan yapılar üretme konusunda bütün diğer 3B baskı modellerinden önde olsa da biyoyazıcı olarak değerlendirilmemiştir. Bu çalışma da bu başarılmaya çalışılmış ve üretilmiş olan kalp kapakçıklarının biyouyumluluk özellikleri incelenmiştir.

Anahtar kelimeler


Stereolitografi; 3B yazıcı; biyoyazıcı; yapay kalp kapakçığı

Tam metin:

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